AntiDepressants Expert

Depression – a serious and widespread disease, which sometimes can lead to disability. Gives us hope that fact that over time in this disease often comes improvement. Depression often occurs on the background of the various stresses of life – a change of residence, problems in family and marital life, problems at work and others. It may be associated with medical problems or the presence of chronic physical disease, especially accompanied by severe pain.

There are various treatments that reduce the duration of depression. As life stress and health problems can lead to an imbalance in the exchange of neurotransmitters in the nervous system.
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The first drugs that have received the application as a specific means of treatment for depression, appeared in the late 50-ies of the century.

In 1996 about 13 million Americans take antidepressants. And it’s 6% of the whole earth population. This figure rose to 10% (27 million) by 2005. Antidepressants now takes more than just Americans, but those who took drugs before, started getting them in large quantities. In 2008 there were 164 million prescriptions written out: all this cost patients $ 9.6 billion dollars. The researchers examined data on health surveys conducted by U.S. Agency for Health Research and Quality.
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One in four caregivers for ill or elderly relatives and friends said in a survey released on Tuesday that they suffer from depression, a figure far higher than for the U.S. population in general.

By comparison, 9 percent of all Americans are estimated to suffer from depression, according to a study released last year by the U.S. Centers for Disease Control and Prevention in Atlanta.
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Some patients with breast cancer who are taking tamoxifen may not get the full benefit of the drug treatment if they are also taking antidepressants, researchers said here on March 25 at the 7th European Breast Cancer Conference (EBCC7).

Recent literature has pointed to the importance of the CYP2D6 enzyme system in the activation of tamoxifen to its more active metabolite endoxifen. In addition to some patients being poor metabolisers of tamoxifen, medications such as fluoxetine and paroxetine can lead to additional inhibition of this important enzyme and affect breast cancer therapy. Read the rest of this entry »

A recent study published in the American Journal of Obstetrics & Gynecology revealed that pregnant women who take selective serotonin reuptake inhibitors (SSRIs) during their second or third trimesters are five times more likely to have a premature delivery than those not taking them. Such antidepressant drugs include sertraline (Zoloft), paroxetine (Paxil), and fluoxetine (Prozac).

Researchers also found that pregnant women who take benzodiazepines, a type of psychoactive anti-anxiety drug, at any point during their pregnancies are also at a higher risk of having a premature delivery. Their babies are also more likely to be born underweight with respiratory and other health problems. Read the rest of this entry »